BASIC SERVICE PACKAGE

The EpiQuest™ DNA Methylation Analysis Platform combines BaseClear's Next-Gen sequencing with Zymo's well-established bisulfite technologies for the most comprehensive DNA methylation analysis service available. Streamlined sample prep, cutting-edge bioinformatics, and consolidated data delivery take the difficulty out of methylation characterization and simplify epigenetic biomarker discovery.
 
Pricing
For pricing information and a personalized quote, please inquire via our contactform. Discounts are available for volume orders.
 
Turnaround
Fast results, projects are usually completed in 4-5 weeks for most samples.
 
Services Performed

• Genomic DNA Sample Validation 
• Sample Processing and Library Preparation
          1. Endonuclease Digestion
          2. End Modification
          3. Adaptor Ligation
          4. Bisulfite Conversion
          5. Limited Amplification
• Next-Gen Sequencing 
• Sequencing Validation and Bioinformatic Analysis 
• Data Delivery 

Output and Deliverables

• Genome browser tracks
          1. CpG Track
          2. Endonuclease-digested Fragment Track
          3. Next-Gen Sequencing Read Track 
• Aligned next-gen sequencing data 
• Raw data available upon request, but alignment is performed using our proprietary algorithm 

Full Service
The Full Service package removes all complication from methylome sequencing - simply submit DNA samples and receive high-quality data from our comprehensive bioinformatic analysis. This package is recommended for customers without an extensive bioinformatics background.
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Customizable Service
EpiQuest™ service can be adapted to fit the needs of the investigator. There are many options for difficult samples, extra bioinformatic analysis, locus-specific validations, different organisms, and more.
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