- Gene synthesis
- - In-house or OEM
- - Gene optimisation
- - Download sheet
Erwin van Rijn
Together with Derek Butler, Erwin is responsible for BaseClear's Gene to Protein services. He focuses mainly on gene synthesis, synthetic library construction, and cloning and primer synthesis. Erwin manages the team of technicians who carry out the laboratory work and solve any problems that might arise. In addition to this, he maintains the contacts with customers about these services.
CALL +031 (0)71 523 3917
MAIL info@baseclear.nl
Gene synthesis service
BaseClear offers De Novo gene synthesis. This is an extremely fast and efficient way to obtain and/or optimise any possible DNA sequence, from a few hundred base pairs up to several kb.
Send us a digital version of the sequence that you want and we will deliver to you the requested gene, cloned into a standard vector.
In-house or OEM
We can perform the gene synthesis in-house, or we can outsource the synthesis to our OEM gene manufacturer Bio Basic. In both cases we guarantee the same quality and confidentiality. The service options differ only in price and delivery time.
Gene optimisation
Prior to gene synthesis, we can optimise the sequence to increase the final gene expression. Using a special computer program we can eliminate rarely used codons and favour codons that are dominant in the expression host of your choice. In addition to this, we can add or remove restriction sites, eliminate repeats, splice sites and motives and avoid RNA secondary structures. Click here to find more information about our codon optimisation program.
Options:
- In-house gene synthesis: In-house synthesis and optimisation of a synthetic DNA fragment.
- OEM gene synthesis (Bio Basic): OEM synthesis and optimisation of a synthetic DNA fragment.
- Additional option: subcloning of a synthetically produced DNA-fragment into a customer specified vector.
- Additional option: expression of the synthesised gene and purification of the corresponding protein.
Note: Minimal order quantity for gene synthesis is € 200,-
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