- Genetic variation analysis
- - Customised services
- - Full service
- - Download sheet
Monika Hidding
Monika works at Baseclear as forensic expert and genotyping specialist.
CALL +031 (0)71 523 3917
MAIL info@baseclear.nl
Genetic variation analysis
BaseClear offers a broad package of services for the analysis of genetic variations. BaseClear has the technical tools and scientific capabilities to, for example, screen for mutagenesis, single or multiple SNPs, and tandem repeat numbers (VNTR or STR).
Genetic variations can affect the development of diseases and the response to pathogens and drugs. The study of such variations is also important in other research fields, such as crop and livestock breeding programs. Genetic variations may be present naturally or have been introduced by genetic modification.
Customised services
We offer various custom genetic variation analysis services, based on a number of techniques. Both low and high throughput screening projects can be conducted, based on standard or newly designed assays. Genotyping can be performed both for known genetic variations and for new, undiscovered mutations. Our interactive project management will ensure that all your ideas will be taken into account. In case of a newly designed assay, we will store the assay in order to enable our customers to ship new series of samples for subsequent screening.
Full service including DNA purification and primer design
Samples may be delivered as purified DNA or as raw material. BaseClear has fully automated systems to isolate and quantify DNA from various sources in high throughput format. Primers may be provided by the customer or designed and synthesised by BaseClear.
Options
- SNP discovery. Discovery of putative SNP's by DNA sequencing.
- SNP analysis sequencing. Detection of known SNP's by DNA sequencing.
- VNTR/STR analysis. Analysis of variable number tandem repeats (VNTR) or short tandem repeats (STR) by automated fluorescent fragment analysis.
- Genotyping of mouse tails. PCR analysis on DNA isolated from mouse tails, for example to check for a knockout.
- Fragment analysis. Analysis of DNA fragment length by high-resolution gel electrophoresis, capillary electrophoresis or standard agarose gel analysis.
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