BaseClear BiaNomics offers complete solutions to help determine the effect of cosmetics, soaps, personal care products, antibiotics, probiotics or other interventions on the skin microbiome. This analysis is required to put a ‘microbiome friendly’ claim on a product or to demonstrate the efficacy of a product. BaseClear BiaNomics offers services for the entire process including sampling, logistics, sample preparation, collection
of metadata, downstream bioinformatics and statistical analysis.

BaseClear BiaNomics also provides consultancy and support for project design. Our product specialists can advise you regarding sampling, sample preparation and the best technical approach to use. We respond fast to inquiries and our focus is to deliver results as fast as possible.

HOW DOES YOUR PRODUCT WORK ON THE SKIN MICROBIOME?

The human skin is home to millions of bacteria, fungi and viruses, which compose the skin microbiota. The skin microbiota is extremely important to the skin health and it plays an essential role in skin protection against external infectious or toxic substances.

It is important to maintain the balance of the skin microbiota in order to preserve the best physiology of the skin. Skin microbial communities are largely stable over time, despite the exposure of the skin to different external environments. However the skin microbiome can be affected by for instance personal care products, antibiotics, cosmetics, soaps and nutrition.

The clinical proof of your product efficacy BaseClear BiaNomics offers a complete solution to demonstrate the real efficacy of your product on the microbiome. Our specialists can give consultancy and support for project design, and we deliver complete reports including optional in-depth bioinformatics analysis.

Contact BiaNomicsRequest quotation
Skin microbiome analysis

We translate skin microbiome data to clear results

The BaseClear BiaNomics team includes a number of experienced PhD-level molecular biologists, microbiome specialists and bioinformatics experts. Get in touch with one of our experts to discuss your project or to learn more about our microbiome analysis solutions.

Contact our specialist

SAMPLING AND LOGISTICS FOR SKIN MICROBIOME ANALYSIS PROJECTS

BaseClear BiaNomics can help you with the logistics of your research. We offer a non-invasive sampling collection kits that contain all the necessary materials to collect the sample. The kit contains specific instructions for sampling, making sure the sampling is done correctly and uniform. The samples are sent directly back to us for analysis in a standardized way. Besides offering our standard sample collection kit, we can also customize the branding of the kit itself and its contents to suit the needs of your specific project.

Contact usRequest quotation
Sampling box BiaNomics

DNA AND/OR RNA EXTRACTION FROM SKIN SAMPLES

BaseClear BiaNomics has optimized and validated extraction procedures to extract DNA and RNA from complex samples, such as swabs from skin with low biomass. DNA/RNA extraction is an essential step in skin microbiome analysis projects, since the analysis has no value if the DNA of the different organisms do not represent the actual microbial community. The extraction method can have a strong influence on the quantification of the total bacteria and the abundance estimations of specific groups.

Read moreContact our specialist
DNA extraction wutg the microbiomics products from Zymo Research

Statistics

Typically, the data coming from microbial community studies are high-dimensional and together with associated meta-data can be used to unravel the relation between the microbial composition and/or function with environmental variables or sample characteristics. Using multivariate analyses BaseClear can mine data to stratify individuals in, for example, responders and non-responders based on the abundances of different microbial groups or functional identifiers as well as indicate if the different sample group are significantly different. Furthermore, this analysis facilitates identification of microbial groups or function identifiers that are important drivers of the difference between sample groups.

Contact BiaNomics
Multivariate analysis

Meet Tom van den Bogert!

Tom is responsible for metagenomics and microbial profiling projects, which are based on our next generation sequencing technologies, and the development of related approaches.

Contact Tom

Convinced? Get in touch

Get a quoteMeet baseClearContact form