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Clinical trials represent the bridge needed to transform microbiome hypotheses and potential applications into real-world benefits. Microbiome analysis is at the forefront of clinical trials designed to assess novel therapeutics (e.g. fecal microbiota transplantation, phagotherapy, antimicrobial peptides and therapeutic adjuvants) and is also a major point of interest for the food industry. There is increasing awareness of the potential detrimental effects of antibiotics on the gut microbiome, and the need to consider effects on antibiotic resistance when developing new therapeutics.
BaseClear partners with leaders of large-scale clinical trials, who are focused on unravelling these key aspects of microbiome research. For example, we have collaborated with Caelus Health to help them determine how a bacterium, Eubacterium hallii, increases insulin sensitivity in people with Metabolic Syndrome. BaseClear facilitates clinical microbiome research largely through the shotgun profiling of faecal samples and bioinformatics expertise.
Get in touch with the BaseClear experts to discuss your specific project.