Partnership in clinical trials

Clinical trials represent the bridge needed to transform microbiome hypotheses and potential applications into real-world benefits. Microbiome analysis is at the forefront of clinical trials designed to assess novel therapeutics (e.g. fecal microbiota transplantation, phagotherapy, antimicrobial peptides and therapeutic adjuvants) and is also a major point of interest for the food industry. There is increasing awareness of the potential detrimental effects of antibiotics on the gut microbiome, and the need to consider effects on antibiotic resistance when developing new therapeutics.

BaseClear solutions for clinical trials

BaseClear partners with leaders of large-scale clinical trials, who are focused on unravelling these key aspects of microbiome research. For example, we have collaborated with Caelus Health to help them determine how a bacterium, Eubacterium hallii, increases sensitivity in people with Metabolic Syndrome. BaseClear facilitates clinical microbiome research largely through the shotgun profiling of faecal samples and bioinformatics expertise.


• State-of-the-art microbiome research through all stages of the clinical trial process from design and conduct of the trial right through to the final report.
• Our expert research team will work with sponsor(s) and researchers to design and conduct a study most suitable for their project.
• Extensive microbiome sampling and analysis including strain tracking using qPCR, 16S and shotgun sequencing, metatranscriptomics, virome & phage analysis, metabolomics  and in-depth bioinformatics and biostatistics.
• Supporting trials to support health claim & mechanistic studies on a variety of products, ranging from probiotics, prebiotics, fibres and a range of other substrates.
• We can statistically power your study to ensure that your objectives are achieved.
• Working with a range of sample types, including faeces, urine, tissue, biopsies and swabs.



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