Epigenetic regulation refers to biological mechanisms in which DNA, RNA, and proteins are chemically or structurally modified, without changing their primary sequence. These epigenetic modifications play critical roles in the regulation of numerous cellular processes, including gene expression, DNA replication, and recombination. Epigenetic regulatory mechanisms include DNA methylation and hydroxymethylation, histone modification, chromatin remodeling, RNA methylation, and regulation by small and long non-coding RNAs.
While epigenetic modifications can be very stable and passed on to multiple generations in some cases, they can also dynamically change in response to specific cellular conditions or environmental stimuli. When epigenetic mechanisms are misregulated, the result can be detrimental to health and can lead to cancer, neurological disorders, and developmental abnormalities. Therefore, epigenetic modifications are emerging as important diagnostic and prognostic biomarkers in many fields of medicine.
In recent years, epigenetics has exploded into one of the most exciting and rapidly expanding fields in biology. Zymo Research has grown with it, becoming The Epigenetics Company™. Zymo Research understands the need for high-quality and reliable products for epigenetics research, and we offer an extensive and continually growing line of products, kits, and genome-wide services to facilitate investigations into epigenetic regulation of cellular processes. We are committed to continue meeting the needs of epigenetic researchers into the future.
DNA methylation remains one of the most extensively studied areas of epigenetic research, and Zymo Research’s products for investigating DNA methylation are the most cited and trusted in the industry.
DNA hydroxymethylation is an epigenetic modification that is being increasingly investigated, yet its biological remains unclear.
Zymo Research assists scientists in pioneering the emerging field of RNA epigenetics with the first commercially available products to study methylation in RNA Chromatin Analysis Products for the analysis of chromatin and nucleosome-associated DNA
Zymo Research offers the best purification kits for investigating small (miRNA, siRNA, piRNA) and long non-coding RNAs.
ANTIBODIES FOR EPIGENETICS
Antibodies are essential for many epigenetic experiments, and Zymo Research offers some of the most specific and sensitive epigenetic antibodies available.
EPIGENETIC ENZYMES AND REAGENTS
Zymo Research offers an extensive line of enzymes and reagents for use in epigenetic experiments
For the complete overview of Zymo Research Epigenetic products, please visit http://www.zymoresearch.com/epigenetics
Free DNA Methylation sample kits available for evaluation, click here >>
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