Generate population-scale genomic data at unprecedented scale and cost efficiency through fully automated Ultima Genomics workflows and integrated sample-to-data tracking.
Ultima Genomics Sequencing for High-Volume Data Generation enables researchers and technology providers to generate genomic data at unprecedented scale and cost efficiency. By combining the Ultima Genomics platform with BaseClear’s automated laboratory workflows, integrated sample tracking, and expert project management, clients can execute large-scale sequencing projects without investing in their own sequencing infrastructure. The service is designed for projects where data volume, reproducibility, and operational scalability are critical.
The service is currently focused on two key customer groups. First, companies that have established single-cell library preparation workflows and require a reliable sequencing partner capable of delivering high-throughput sequencing capacity. In these projects, BaseClear acts as a dedicated sequencing provider, generating high-quality sequencing data from client-supplied libraries. Second, organizations conducting large-scale genomics studies, biobank initiatives, or population research projects that are primarily seeking the most cost-efficient route to large volumes of sequencing data. For these clients, BaseClear provides both library preparation and sequencing as an integrated service to ensure optimal data quality, workflow consistency, and scalability.
The workflow combines Ultima Genomics’ high-throughput sequencing technology with state-of-the-art laboratory automation and digital infrastructure. Samples are processed using automated library preparation workflows on Tecan platforms, while LabWare LIMS provides full sample traceability and project visibility from collection through data delivery. Depending on project requirements, BaseClear can support sample intake, DNA isolation, library preparation, sequencing, quality control, and bioinformatics processing. This fully integrated approach minimizes manual handling, increases reproducibility, and enables efficient processing of large sample cohorts.
Clients receive high-quality sequencing data together with comprehensive quality control documentation and project reporting. Deliverables can include raw sequencing data (FASTQ files), quality metrics, demultiplexed datasets, and project-specific data packages tailored to downstream analysis requirements. For single-cell providers, deliverables focus on reliable, high-throughput sequencing output compatible with their existing analytical workflows. For large-scale genomics projects, BaseClear can additionally provide sample management, library preparation reporting, sequencing performance metrics, and integrated project tracking through its digital infrastructure, creating a complete sample-to-data solution.
Discuss your project objectives, sample or library type, expected data volume, turnaround requirements, and data delivery needs with our sequencing specialists. Together, we define the most efficient workflow for your project.
Single-cell providers can submit sequencing-ready libraries directly to BaseClear, while large-scale genomics projects can submit biological samples for integrated library preparation and sequencing. Our team ensures all materials are received, tracked, and prepared for processing.
For projects requiring sample processing, BaseClear performs automated library preparation using validated workflows and Tecan automation platforms. Quality control steps are incorporated to ensure consistent performance across large sample batches.
Libraries are sequenced on the Ultima Genomics platform using fully automated workflows designed for large-scale data generation. Throughout the project, sample status and progress can be monitored through our integrated LabWare LIMS infrastructure.
Receive high-quality sequencing data together with quality metrics, project documentation, and secure data transfer. Depending on project requirements, deliverables can include raw sequencing data, demultiplexed datasets, QC reports, and project-specific data packages.
Basecamp Research set out to create the Trillion Gene Atlas, an ambitious initiative designed to generate and model biological data at unprecedented scale. The project required a sequencing partner capable of delivering massive sequencing throughput while maintaining operational scalability, sample traceability, workflow consistency, and efficient project execution across large numbers of samples.
To support this initiative, Basecamp Research partnered with BaseClear to provide high-throughput sequencing on the Ultima Genomics UG200 platform. In addition to sequencing, BaseClear implemented an integrated LabWare LIMS solution to enable end-to-end sample tracking and project visibility, developed automated library preparation workflows using Tecan automation platforms to support scalable processing, and provided dedicated project management to coordinate sequencing operations, workflow optimization, data delivery, and communication throughout the project lifecycle.
By combining Ultima Genomics sequencing technology with automated laboratory workflows, integrated digital infrastructure, and dedicated project management, BaseClear established a scalable sample-to-data workflow capable of supporting one of the largest genomics initiatives ever undertaken. The project demonstrates how cost-efficient, high-throughput sequencing can enable genomic data generation at a scale that was previously impractical.
End-to-end microbial safety assessment capabilities
Regulatory-ready data generation and interpretation
Integrated wet-lab and bioinformatics expertise
Structured support for EFSA and global submissions
Ultima Genomics sequencing is particularly well suited for projects that require the generation of very large amounts of sequencing data at the lowest possible cost per sample or per gigabase. Typical applications include single-cell sequencing programs, population genomics studies, pharma genomics initiatives, biobanking projects, large cohort studies, and other high-throughput sequencing applications where scalability and cost efficiency are critical.
BaseClear supports both sequencing-only workflows and fully integrated library preparation plus sequencing services. Single-cell technology providers and other organizations with established library preparation workflows can submit sequencing-ready libraries directly, while clients seeking a complete sample-to-data solution can leverage BaseClear’s automated library preparation workflows, sequencing services, quality control, and project management expertise.
BaseClear ensures consistency through a combination of laboratory automation, standardized workflows, integrated sample tracking, and comprehensive quality control procedures. Automated library preparation on Tecan platforms reduces manual variability, while the LabWare LIMS infrastructure provides full traceability from sample receipt through data delivery, enabling reproducible processing across large sample cohorts and multiple sequencing batches.
Ultima sequencing projects include comprehensive quality control documentation covering library quality, sequencing performance, sample tracking, and data delivery metrics. Depending on project requirements, clients can receive information on library concentrations, fragment size distributions, sequencing yield, read quality, demultiplexing performance, sample success rates, and run-level quality metrics to support downstream analysis and regulatory documentation requirements.
BaseClear combines high-throughput Ultima Genomics sequencing with automated laboratory workflows, integrated digital infrastructure, and dedicated project management. Rather than acting solely as a sequencing vendor, BaseClear provides a complete operational framework including automated library preparation, LabWare-based sample tracking, secure data delivery (ISO27001 certified), and expert project coordination, enabling customers to scale complex genomics programs without building their own sequencing operations.
SERVICES
Phenotypic assessment of antimicrobial resistance aligned with EFSA guidelines
SERVICES
Phenotypic assessment of antimicrobial and cytotoxic production
Speak with our experts to design a WGS strategy aligned with your regulatory needs. Your first consultation is free and without obligation.
