Based on optimised protocols, BaseClear is able to create mutations in virtually every DNA fragment. This is a valuable tool for studying DNA or protein structure and function. Site-directed or random mutagenesis can be applied to any DNA-fragment cloned into a plasmid vector. We can help you to introduce a range of mutations, varying from point mutations to deletions or insertions. The final construct will be delivered as purified plasmid DNA of your vector with the mutation in combination with an E. coli stab containing this plasmid. The samples will be accompanied by a report of the mutagenesis project, including the raw sequencing data and a complete alignment of the sequence around the mutation.