Advanced Sequencing Solutions

From fast-track sequencing to hybrid genomics and transcriptomics, BaseClear combines cutting-edge sequencing platforms, automated workflows, and expert data analysis to deliver high-quality results when speed and insight matter most. 

Advanced Sequencing Solutions for Faster, Deeper Genomic Insights

Advanced Sequencing Solutions are designed for projects that require more than standard sequencing services, whether the goal is faster results, deeper genomic resolution, comprehensive transcriptomic insights, or rapid genome characterization. These services support biotechnology, biopharmaceutical, food, feed, industrial, and academic organizations that need high-quality genomic data to accelerate research, development, product characterization, strain improvement, process optimization, and critical decision-making. 

BaseClear combines leading sequencing technologies, including Illumina short-read and Oxford Nanopore long-read sequencing, with automated laboratory workflows, advanced bioinformatics, and over 30 years of genomics expertise. Our portfolio includes fast-track sequencing through TurboSeq, integrated long-read and short-read Hybrid Sequencing, RNA-Seq for gene expression analysis, and Genome in a Week for rapid microbial genome characterization. By tailoring the sequencing strategy to each project, BaseClear delivers reliable, actionable data with the speed, quality, and scientific support needed to move projects forward with confidence. 

Services

Why BaseClear

Faster Scientific Decisions

Receive high-quality genomic data in as little as 5 business days, enabling faster project progression, shorter development cycles, and earlier go/no-go decisions. 

More Insight per Sample

Choose from transcriptomics, hybrid sequencing, rapid genome sequencing, or ultra-scale genomics to generate the level of biological insight your project requires without paying for unnecessary complexity. 

One Trusted Partner

Work with a single genomics partner for sequencing, bioinformatics, project management, and data delivery, supported by 30+ years of experience and proven laboratory automation workflows. 

Related resources

Frequently Asked Questions

How do I choose between TurboSeq, UltraScale Sequencing, Hybrid Sequencing, and RNA-Seq?

The best sequencing solution depends on the biological question, timeline, and data requirements of the project. TurboSeq is designed for rapid turnaround, UltraScale Sequencing for large-scale and cost-efficient data generation, Hybrid Sequencing for maximum genomic resolution through combined short- and long-read sequencing, and RNA-Seq for gene expression profiling and transcriptomic analysis. BaseClear works with clients to select the most appropriate workflow based on project goals, sample type, budget, and desired outcomes. 

Hybrid Sequencing provides advantages when both high accuracy and long-range genomic information are required. By combining Illumina short reads with Oxford Nanopore long reads, the approach improves genome assembly quality, resolves repetitive genomic regions, enhances taxonomic classification, and supports more detailed interpretation of complex microbial communities and genomes than either technology alone. 

Turnaround times vary depending on the sequencing solution selected and the complexity of the project. Genome in a Week can deliver assembled microbial genomes within five business days, while TurboSeq provides high-quality sequencing data in as little as one week from sample receipt. Larger projects involving RNA-Seq, Hybrid Sequencing, or UltraScale Sequencing may require additional analysis time depending on study size and deliverables. 

Every Advanced Sequencing Solution includes quality control measures throughout sample processing, library preparation, sequencing, and bioinformatics analysis. Depending on the service, clients receive detailed QC metrics such as DNA or RNA quality assessments, library quality statistics, sequencing yield, read quality metrics, control performance, and bioinformatics QC summaries to ensure that generated data meet predefined acceptance criteria. 

Advanced Sequencing Solutions provide both raw sequencing data and project-specific analytical outputs tailored to the scientific objectivesDepending on the selected service, deliverables may include FASTQ filesgenome assembliestranscriptomic datasets, gene expression tables, variant analyses, taxonomic profilespublication-ready visualizationscomprehensive reportsand expert interpretation to support research, development, quality control, and regulatory activities. 

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