From fast-track sequencing to hybrid genomics and transcriptomics, BaseClear combines cutting-edge sequencing platforms, automated workflows, and expert data analysis to deliver high-quality results when speed and insight matter most.
Advanced Sequencing Solutions are designed for projects that require more than standard sequencing services, whether the goal is faster results, deeper genomic resolution, comprehensive transcriptomic insights, or rapid genome characterization. These services support biotechnology, biopharmaceutical, food, feed, industrial, and academic organizations that need high-quality genomic data to accelerate research, development, product characterization, strain improvement, process optimization, and critical decision-making.
BaseClear combines leading sequencing technologies, including Illumina short-read and Oxford Nanopore long-read sequencing, with automated laboratory workflows, advanced bioinformatics, and over 30 years of genomics expertise. Our portfolio includes fast-track sequencing through TurboSeq, integrated long-read and short-read Hybrid Sequencing, RNA-Seq for gene expression analysis, and Genome in a Week for rapid microbial genome characterization. By tailoring the sequencing strategy to each project, BaseClear delivers reliable, actionable data with the speed, quality, and scientific support needed to move projects forward with confidence.
BaseClear’s Ultima platform delivers ultra-high-throughput sequencing for projects that require large-scale genomic analysis, exceptional data volumes, and cost-efficient sequencing at scale. Powered by the Ultima Genomics UG200 platform and supported by automated library preparation, advanced bioinformatics, and dedicated scientific expertise, clients benefit from high-quality sequencing data, scalable project execution, and a future-ready solution for applications such as whole genome sequencing, population genomics, single cell, transcriptomics, metagenomics, and large research initiatives.
TurboSeq is BaseClear’s accelerated next-generation sequencing service designed for projects where turnaround time directly impacts development decisions, validation timelines, and project milestones. Powered by proven Illumina NextSeq technology and optimized laboratory workflows, TurboSeq delivers high-quality, decision-ready sequencing data in as little as one week from sample receipt without compromising data quality or scientific rigor. The service is particularly suited for sensitive detection studies, residual DNA and contamination analysis, validation and verification workflows, custom assay development, and projects with limited internal sequencing capacity. Clients receive quality-controlled sequencing data, expert scientific support, and a reliable fast-track service that helps reduce bottlenecks, accelerate decision-making, and keep critical programs on schedule.
Hybrid Sequencing combines the strengths of Illumina short-read and Oxford Nanopore long-read sequencing to deliver a more complete and accurate view of complex biological samples. By sequencing the same DNA sample on both platforms, BaseClear generates highly reliable quantitative data alongside enhanced taxonomic resolution, improved genome reconstruction, and deeper biological insights that cannot always be achieved with a single sequencing technology. This approach is particularly valuable for microbiome studies, microbial genomics, strain tracking, and other applications where both accuracy and genomic context are critical. Clients receive integrated sequencing results, comprehensive quality control reporting, advanced bioinformatics analyses, and actionable insights that support confident interpretation of complex genomic and microbiome datasets.
Genome in a Week is BaseClear’s ultra-fast microbial whole genome sequencing service, delivering fully assembled and annotated genomes within five business days. Powered by Oxford Nanopore long-read sequencing and validated in-house bioinformatics pipelines, the service enables rapid characterization of bacteria, yeasts, fungi, phages, viruses, and plasmids for applications such as strain characterization, pathogen analysis, antimicrobial resistance profiling, quality control, and regulatory submissions. Clients receive raw sequencing data, a fully assembled and annotated genome, and a comprehensive report, providing actionable genomic insights with industry-leading turnaround times and the support of a team with more than 30 years of microbial genomics expertise.
Receive high-quality genomic data in as little as 5 business days, enabling faster project progression, shorter development cycles, and earlier go/no-go decisions.
Choose from transcriptomics, hybrid sequencing, rapid genome sequencing, or ultra-scale genomics to generate the level of biological insight your project requires without paying for unnecessary complexity.
Work with a single genomics partner for sequencing, bioinformatics, project management, and data delivery, supported by 30+ years of experience and proven laboratory automation workflows.
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The best sequencing solution depends on the biological question, timeline, and data requirements of the project. TurboSeq is designed for rapid turnaround, UltraScale Sequencing for large-scale and cost-efficient data generation, Hybrid Sequencing for maximum genomic resolution through combined short- and long-read sequencing, and RNA-Seq for gene expression profiling and transcriptomic analysis. BaseClear works with clients to select the most appropriate workflow based on project goals, sample type, budget, and desired outcomes.
Hybrid Sequencing provides advantages when both high accuracy and long-range genomic information are required. By combining Illumina short reads with Oxford Nanopore long reads, the approach improves genome assembly quality, resolves repetitive genomic regions, enhances taxonomic classification, and supports more detailed interpretation of complex microbial communities and genomes than either technology alone.
Turnaround times vary depending on the sequencing solution selected and the complexity of the project. Genome in a Week can deliver assembled microbial genomes within five business days, while TurboSeq provides high-quality sequencing data in as little as one week from sample receipt. Larger projects involving RNA-Seq, Hybrid Sequencing, or UltraScale Sequencing may require additional analysis time depending on study size and deliverables.
Every Advanced Sequencing Solution includes quality control measures throughout sample processing, library preparation, sequencing, and bioinformatics analysis. Depending on the service, clients receive detailed QC metrics such as DNA or RNA quality assessments, library quality statistics, sequencing yield, read quality metrics, control performance, and bioinformatics QC summaries to ensure that generated data meet predefined acceptance criteria.
Advanced Sequencing Solutions provide both raw sequencing data and project-specific analytical outputs tailored to the scientific objectives. Depending on the selected service, deliverables may include FASTQ files, genome assemblies, transcriptomic datasets, gene expression tables, variant analyses, taxonomic profiles, publication-ready visualizations, comprehensive reports, and expert interpretation to support research, development, quality control, and regulatory activities.
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