Explore the advanced sequencing, molecular biology, automation, and data management platforms that power BaseClear’s high-quality analytical and genomics services.
BaseClear’s Technology Platforms provide clients with access to a comprehensive portfolio of advanced sequencing, molecular biology, automation, and laboratory information management technologies. Whether supporting microbial genomics, biopharmaceutical development, quality control, strain characterization, contamination testing, or large-scale research projects, these platforms enable the generation of accurate, reliable, and actionable data. Clients benefit from access to the most appropriate technology for their specific application, ranging from high-throughput sequencing and long-read analysis to highly sensitive nucleic acid quantification and automated laboratory workflows.
What makes BaseClear distinctive is the integration of these technologies within a single organization, supported by experienced scientists, bioinformaticians, and project managers. Rather than offering individual instruments or standalone services, we combine leading platforms such as Ultima, Illumina, Oxford Nanopore, Sanger sequencing, dPCR, qPCR, Tecan automation, and LabWare LIMS to create efficient, scalable, and fit-for-purpose workflows. This integrated approach delivers high-quality data, improved turnaround times, full traceability, and a seamless customer experience from sample receipt to final results.
BaseClear’s Ultima platform delivers ultra-high-throughput sequencing for projects that require large-scale genomic analysis, exceptional data volumes, and cost-efficient sequencing at scale. Powered by the Ultima Genomics UG200 platform and supported by automated library preparation, advanced bioinformatics, and dedicated scientific expertise, clients benefit from high-quality sequencing data, scalable project execution, and a future-ready solution for applications such as whole genome sequencing, population genomics, single cell, transcriptomics, metagenomics, and large research initiatives.
BaseClear’s digital PCR (dPCR) platform provides highly sensitive and accurate detection and quantification of nucleic acid targets for biopharmaceutical, microbial, and life sciences applications. The platform is particularly suited for applications such as residual host cell DNA analysis, viral titer determination, vector copy number analysis, contamination testing, and assay validation, where precision and reproducibility are critical. Supported by validated GMP workflows, experienced scientists, and regulatory-ready documentation, clients receive reliable quantitative results, full traceability, and expert support to meet quality, development, and regulatory requirements.
BaseClear’s quantitative PCR (qPCR) platform provides sensitive, reliable, and cost-effective detection, identification, and quantification of nucleic acid targets across biopharmaceutical, microbial, and life sciences applications. The platform supports applications such as microbial detection, viral analysis, contamination testing, residual DNA quantification, product characterization, and routine quality control testing. Supported by validated GMP workflows, LabWare LIMS, integrated Electronic Laboratory Notebook (ELN) systems, and experienced scientific staff, clients receive accurate results, complete traceability, regulatory-ready documentation, and rapid turnaround times.
Illumina sequencing is the industry standard for high-accuracy next-generation sequencing and is widely used for applications ranging from microbial genomics and metagenomics to biopharmaceutical quality control and research. BaseClear’s Illumina platform supports applications such as whole genome sequencing, targeted sequencing, RNA-seq, microbial characterization, viral identification, and adventitious agent testing, delivering highly accurate and reproducible results. Combined with automated laboratory workflows, advanced bioinformatics, GMP-compliant services, and dedicated scientific support, clients receive high-quality sequencing data, actionable insights, and regulatory-ready documentation tailored to their specific project objectives.
Oxford Nanopore Technologies (ONT) enables real-time, long-read sequencing, providing unique insights into complex genomes, structural variants, plasmids, viral genomes, and transcriptomes that are difficult to resolve with short-read technologies alone. BaseClear’s ONT platform supports applications such as de novo genome assembly, hybrid sequencing, microbial characterization, plasmid verification, transcriptomics, and metagenomics, delivering comprehensive genomic information with rapid turnaround times. Combined with automated workflows, advanced bioinformatics, and experienced scientific support, clients benefit from greater genomic resolution, flexible project design, and deeper biological insights tailored to their research or development objectives.
Sanger sequencing has been the foundation of BaseClear’s genomics services since 1992 and remains a trusted technology for accurate DNA sequence verification and targeted genetic analysis. Our Sanger platform supports applications such as plasmid and vector confirmation, clone verification, microbial identification, mutation analysis, and sequence validation, providing highly reliable results for both research and regulated environments. Supported by our GMP license, experienced scientific team, and robust quality systems, clients receive accurate sequence data, rapid turnaround times, full traceability, and regulatory-ready documentation when required.
LabWare is the digital backbone of BaseClear’s laboratory operations, providing comprehensive laboratory information management, sample tracking, workflow control, and data management across all services. Integrated with our laboratory instruments, quality systems, and Electronic Laboratory Notebook (ELN) platform, LabWare ensures complete sample traceability, secure data storage, audit-ready documentation, and real-time project visibility. Clients benefit from improved transparency, data integrity, regulatory compliance, and a seamless experience from sample submission through final reporting.
Tecan automation enables BaseClear to deliver highly standardized, scalable, and efficient laboratory workflows through the use of advanced liquid handling platforms, including the Tecan Fluent 480 and Dreamprep 780. These systems support applications such as sequencing library preparation, sample normalization, pooling, PCR setup, and high-throughput screening, reducing manual handling and improving reproducibility. Clients benefit from increased throughput, consistent data quality, reduced turnaround times, and robust workflow execution supported by automated quality controls and experienced laboratory specialists.
BaseClear offers a broad portfolio of sequencing, PCR, automation, and laboratory information management platforms, including Ultima, Illumina, Oxford Nanopore, Sanger, dPCR, qPCR, Tecan, and LabWare. This allows our scientists to select the most appropriate technology for each project rather than forcing every application onto a single platform.
Our technology platforms are connected through automated laboratory workflows, in-house bioinformatics, and LabWare LIMS and ELN systems. Clients benefit from complete sample traceability, reduced manual handling, improved reproducibility, and a seamless process from sample receipt to final reporting.
The same technology infrastructure supports projects ranging from routine research studies to GMP-compliant biopharmaceutical testing and validation programs. Combined with our GMP license, ISO 17025 accreditation, and ISO 27001 certification, clients can confidently scale projects while maintaining quality, compliance, and data integrity.
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The best sequencing solution depends on the biological question, timeline, and data requirements of the project. TurboSeq is designed for rapid turnaround, UltraScale Sequencing for large-scale and cost-efficient data generation, Hybrid Sequencing for maximum genomic resolution through combined short- and long-read sequencing, and RNA-Seq for gene expression profiling and transcriptomic analysis. BaseClear works with clients to select the most appropriate workflow based on project goals, sample type, budget, and desired outcomes.
Hybrid Sequencing provides advantages when both high accuracy and long-range genomic information are required. By combining Illumina short reads with Oxford Nanopore long reads, the approach improves genome assembly quality, resolves repetitive genomic regions, enhances taxonomic classification, and supports more detailed interpretation of complex microbial communities and genomes than either technology alone.
Turnaround times vary depending on the sequencing solution selected and the complexity of the project. Genome in a Week can deliver assembled microbial genomes within five business days, while TurboSeq provides high-quality sequencing data in as little as one week from sample receipt. Larger projects involving RNA-Seq, Hybrid Sequencing, or UltraScale Sequencing may require additional analysis time depending on study size and deliverables.
Every Advanced Sequencing Solution includes quality control measures throughout sample processing, library preparation, sequencing, and bioinformatics analysis. Depending on the service, clients receive detailed QC metrics such as DNA or RNA quality assessments, library quality statistics, sequencing yield, read quality metrics, control performance, and bioinformatics QC summaries to ensure that generated data meet predefined acceptance criteria.
Advanced Sequencing Solutions provide both raw sequencing data and project-specific analytical outputs tailored to the scientific objectives. Depending on the selected service, deliverables may include FASTQ files, genome assemblies, transcriptomic datasets, gene expression tables, variant analyses, taxonomic profiles, publication-ready visualizations, comprehensive reports, and expert interpretation to support research, development, quality control, and regulatory activities.
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