Obtaining regulatory approval to use microorganisms as food additive or production strain can be challenging. Applying the regulatory guidelines and rules to the genomic data generated when analysing these microbial strains often presents both technical and interpretation challenges. This article …
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Next-Generation sequencing technology is becoming indispensable for many food manufacturers and labs, as it helps them perform safer, faster and more affordable food safety and quality control programs. However, there are still many food companies that are not familiar with …
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A manufacturer of bottled juices for consumption noticed debris in juice bottles as well as a sour, bad odor. Attempts to obtain microbial isolates from the juices for root cause analysis failed. The manufacturer contacted BaseClear to identify the microorganisms that may …
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A Salmonella detection at several production sites in different countries forced a large multinational to perform a root cause analysis. Fast results were essential to limit damages and preventing an outbreak. BaseClear’s strain typing team reported results within 48 hours, minimizing the financial consequences …
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Within BaseClear we are working with Nanopore sequencing since 2014. And in 2017 we became the first certified service provider from Oxford Nanopore Technologies worldwide. Although we are working with this innovative and ground breaking technology for several years now, …
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In my role as account manager at BaseClear I encounter many scientists and R&D managers that cannot see the wood for the trees when it comes to choosing a suitable sequencing platform. For this reason, I wanted to provide a …
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16S rRNA gene based microbial profiling remains an important tool to determine the composition of micro-organisms in a myriad of environmental samples, including faeces, soil, water as well as samples derived from food products (e.g. milk, yogurt, and beer). Though …
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As the costs for sequencing have significantly decreased over the last years the number of whole genome sequencing (WGS) is vastly increasing. Often the end result consists of assembled and annotated genomes. Researchers are required to submit these to the …
Read more During the last decades whole genome and metagenome analysis have provided a wealth of knowledge. However, these studies depend heavily on high-molecular weight, sufficient concentration, adequate quality and unbiased DNA extration methods. As different DNA extraction methods differ in their …
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Microbial communities are the dominant life form on our planet. Even your body hosts as many bacterial cells as it does your own cells. Genomics and bioinformatics tools can unlock this hidden world and allows to explore the microbial diversity, composition …
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BaseClear and RIKILT (Wageningen UR) have recently collaborated to develop innovative methods for GMO traceability. The work was coordinated by Jeroen van Dijk and Marleen Voorhuijzen (RIKILT) within the context of the FP7 European Decathlon project. The preliminary results were …
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Microbial genomics is an essential instrument for understanding microorganisms. Whole genome sequencing delivers a comprehensive view of the entire genome and is often a good starting point when working with a new strain or new type of microorganism. BaseClear offers …
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