Obtaining approval to use microbes as feed or food additive or as a production strain can be challenging. The European (EU / EFSA) and US (US-FDA) regulatory agencies now have strict guidelines for submitting dossiers. Applying the regulatory guidelines and …
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Water, malt, hops, and brewer’s yeast – These are four simple ingredients that when combined create one of the world’s most consumed beverages, beer. In this blog we outline some of the current research about the relationship between the brewer’s …
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As mammals we host a whole set of microbiota ranging from gut to skin, oral and even the lung microbiome. I have provided a brief summary of a couple of up-and-coming microbiota and will touch on why it is imperative …
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Our in-house animal microbiome experts are constantly looking for ways to further their knowledge and understanding of the ever growing field. This week, two of our experts attended a course held at the Wageningen University & Research Centre which focused …
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The microbiome is increasingly making news headlines on a global scale. A rapidly growing number of studies are being published that link the microbiome to phenomenon such as human health and environmental sustainability. And yet, true understanding of what the …
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Check-Points recently obtained FDA clearance for its rapid-screening assay for gram-negative drug-resistant bacteria: BD MAX Check-Points CPO. BaseClear was asked to develop a reference PCR and sequencing method and to serve as reference lab for PCR and Sequencing of bacterial …
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Today, host- and environment-associated microbial communities like those living in the human gut, skin, soil, and water are more and more studied in terms of their functional capacity and activity. For the latter, metatranscriptomics is the method for profiling active …
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Ocean Harvest Technology produces seaweed-based functional feed ingredients for animals. Together with BaseClear, the company is now investigating the effects of its seaweed blend on the animal microbiome and health. “On the market you hear a lot of claims about …
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The Avans University of Applied Sciences in Breda collaborated with BaseClear in an Enabling Technology Hotel (ETH) project for the whole genome sequencing of colistin-resistant bacteria. By combining short-read (Illumina) and long-read (Nanopore) sequencing technologies, the partners succeeded in revealing …
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The Center for Human Drug Research (CHDR) in Leiden is collaborating with BaseClear for microbiome analysis of the skin and the gut in the context of clinical trials. “BaseClear is a partner for us in with regard to technical, scientific …
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Variant detection is an important application of next-generation sequencing experiments. It involves the alignment of sequence reads to a reference and the detection of mutations and other minor variations. While this process may sound simple, in practice many steps and …
Read more While the European (EFSA) and American (FDA) regulatory bodies have established guidelines for the approval of novel microbial strains in food and feed applications, these guidelines are often changed and in some cases are difficult to interpret, making it challenging …
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