Within BaseClear we are working with Nanopore sequencing since 2014. And in 2017 we became the first certified service provider from Oxford Nanopore Technologies worldwide. Although we are working with this innovative and ground breaking technology for several years now, …
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In my role as account manager at BaseClear I encounter many scientists and R&D managers that cannot see the wood for the trees when it comes to choosing a suitable sequencing platform. For this reason, I wanted to provide a …
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16S rRNA gene based microbial profiling remains an important tool to determine the composition of micro-organisms in a myriad of environmental samples, including faeces, soil, water as well as samples derived from food products (e.g. milk, yogurt, and beer). Though …
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As the costs for sequencing have significantly decreased over the last years the number of whole genome sequencing (WGS) is vastly increasing. Often the end result consists of assembled and annotated genomes. Researchers are required to submit these to the …
Read more During the last decades whole genome and metagenome analysis have provided a wealth of knowledge. However, these studies depend heavily on high-molecular weight, sufficient concentration, adequate quality and unbiased DNA extration methods. As different DNA extraction methods differ in their …
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Microbial communities are the dominant life form on our planet. Even your body hosts as many bacterial cells as it does your own cells. Genomics and bioinformatics tools can unlock this hidden world and allows to explore the microbial diversity, composition …
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BaseClear and RIKILT (Wageningen UR) have recently collaborated to develop innovative methods for GMO traceability. The work was coordinated by Jeroen van Dijk and Marleen Voorhuijzen (RIKILT) within the context of the FP7 European Decathlon project. The preliminary results were …
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The application of pharmacogenomics in first line patient care has great potential, but also raises concerns. The potential, the interests of stakeholders and the objections are identified in discussions with experts, doctors, pharmacists, health insurers and representatives of the Ministry …
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Microbial genomics is an essential instrument for understanding microorganisms. Whole genome sequencing delivers a comprehensive view of the entire genome and is often a good starting point when working with a new strain or new type of microorganism. BaseClear offers …
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Have you ever thought of starting a garden on Mars? Perchlorate (ClO4-) contamination is a widely spread hazard for the environment and our health on Earth, but poses even a larger challenge when colonizing our neighbouring red planet Mars. The …
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Flatulence, constipation and diarrhoea are some of the many intestinal problems that we have to deal with. These can be annoying and the cause is often unclear. BaseClear spin-off MyMicroZoo now intends to change this by mapping the inhabitants of …
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PacBio sequencing is often used for sequencing complete microbial genomes. The long reads offer a clear added value to the shorter Illumina reads. Since the sequencing errors on the PacBio platform are basically unbiased, high quality assemblies can be made …
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