Supporting clinical trials

Pre- and clinical trials
BaseClear is your end-to-end partner, guiding you through the entire clinical trial process from study design through sample processing and data analysis to providing a comprehensive report including data interpretation and ready-to-use figures and tables for publication.

Claim substantiation
Our robust claim substantiation services ensure your product’s assertions are supported by solid scientific evidence. Leveraging advanced multi-omics techniques, including taxonomic and functional microbiome profiling, metatranscriptomics, and metabolomics, along with comprehensive data analysis, we provide the necessary support for the claims made during clinical trials.

Tracking of probiotics and quantification
Our tailored qPCR solutions ensure precise tracking and quantification of probiotics, thus enabling accurate monitoring of targeted bacterial populations. This data-driven approach accelerates lead generation, optimizing your research pipeline by identifying high-potential targets and biomarkers for future studies.

Microbiome friendly
Our solutions prioritize the delicate balance of the microbiome, defining microbiome friendliness through a science-led format. This aids regulatory bodies in validating claims and building trust with consumers.

Why BaseClear?

• 1-Stop-Shop
  Streamlined services under one roof, eliminating the need to coordinate with multiple partners, ensuring efficiency and a seamless research experience.
• In-house validated methods
  Rigorous in-house validation methods for bioinformatics pipelines as well as Illumina and ONT procedures, ensuring reliability, accuracy, and compliance with industry regulations.
• Diverse analytical techniques
  Expertise in various techniques, such as qPCR, multi-omics data analysis, robust biostatistics, immune markers, amplicon profiling, and curated databases to meet diverse research needs.
• Data interpretation by PhD scientist
  In-depth data interpretation led by experienced PhD scientists, ensuring a high level of expertise and accuracy in drawing meaningful conclusions from complex datasets.
• Customizability
  Flexibility to incorporate commercial kits or published methods for specialized analyses, providing tailored solutions while leveraging established techniques.
• Continuous communication and support
  Ongoing consultation throughout the entire research process, from covering critical aspects of sample management right to summarizing the study findings in comprehensive reports.

Human Health
BaseClear is at the forefront of supporting diverse studies revealing the microbiome’s impact on human health. Our expertise covers critical areas, such as infant-mother and human gut studies, providing insights into early-life microbial interactions and overall well-being. In clinical trials, we bolster product claims with robust scientific evidence, utilizing advanced techniques like precise probiotic tracking for accurate monitoring.

Skin Health
We support the development of innovative personal care products that maintain the balance and health of the skin microbiome. Our science-led approach in defining microbiome friendliness assists regulatory validation, further fostering consumer trust. Through microbiome analysis, we provide solutions for diverse products, including cosmetics and personal care items for multiple body sites (skin, scalp, oral, vaginal).

Animal Health
Promoting sustainable agricultural practices is central to our commitments to animal health. Partnering in clinical trials on feed efficiency allows us to advance resource-efficient animal farming. Through our innovative metagenomics pipeline, BaseClear supports studies characterizing antibiotic resistance genes in the animal gut. Our in-house methane metabolism bioinformatics pipeline is ideal for studying interventions in ruminants during feeding trials.