Safety assessment of food microbes

The safety of novel foods must be assessed before they are placed on the market within the European Union or USA. The application submitted to the regulatory agencies must include description and detailed composition of the novel food, the production process, and scientific evidence demonstrating that the novel food does not pose safety risk to human health. BaseClear provides support at all steps in the process, whether early-stage research or seeking approval for an already developed novel food.

Microorganisms can only be applied as a food ingredient or production strain if they are sufficiently stable and able to function optimally under the desired conditions. Probiotic bacteria, for example, often need to be able to withstand the gastric acid and bile salts that are present in the stomach and intestines. To investigate and optimize these characteristics, it is necessary to find out which genes are expressed in a given physiological background.

BaseClear offers expert services in particular for food consisting of, isolated from or produced from microorganism (bacteria, fungi or algae) and food consisting of, isolated from or produced from cell culture or tissue culture. We have extensive experience and several PhD-level scientists ready to help in assessing the food microbe safety of the products.

BaseClear services for safety assessment of food microbes

  • Helping in getting data in the form required by the food microbe safety authorities
  • Data analyses, interpretation of results (e.g. from WGS) and conclusions
  • Literature reviews, consultations and statements
  • Whole genome sequencing (WGS), including genome assembly and annotation
  • Metagenomics analysis
  • Identification of microbes (bacteria, yeasts, filamentous fungi)
  • Assessment of genetic stability
  • Analysis of the absence of genetically modified production organism and contaminating recombinant DNA
  • Analysis of the presence of toxin genes and virulence factors
  • Antibiotic resistance genes screening
  • Detection and description of genetic modifications
  • Analysis of secondary metabolite biosynthesis genes
  • Tailored bioinformatics for your specific needs


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